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  • Telmisartan is an angiotensin receptor blocker (ARB) used to treat high blood pressure in cats and off-label to treat kidney disease in both cats and dogs. This medication is given by mouth in the form of a liquid or tablet. It may be given with or without food but is better absorbed if given on an empty stomach. Side effects may include vomiting, diarrhea, lack of appetite, low blood pressure, and decreased energy. There are several drugs that can contribute to adverse effects when given with telmisartan. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Terbinafine oral tablets or granules are commonly used off label to treat skin or systemic fungal infections in dogs and cats. Common side effects are primarily gastrointestinal, such as vomiting, inappetence, and diarrhea, and should be used with caution in patients with liver or kidney disease. If treating with this medication long-term, your veterinarian will perform periodic blood tests to check liver function and monitor for any changes or elevations.

  • Terbinafine cream or spray is occasionally used off label to treat skin fungal infections in dogs, or in a veterinary combination product to treat ear infections. It is ineffective for treating fungal skin infections in cats. When given as directed, side effects are rarely noted, but could include skin irritation.

  • Testicular tumors are generally not aggressive and have a low metastatic rate. Pets with undescended testicles (cryptorchid) are predisposed to the development of certain testicular tumors. Hyperestogenism is possible with Sertoli cell tumors. In any cryptorchid pet, removal of both testicles should be pursued. Intraabdominal tumors in cryptorchid pets may cause lethargy, decreased appetite, and fever. Standard staging is recommended in all cases, including a rectal exam. Surgery is typically the treatment of choice and may be combined with radiation therapy or chemotherapy if metastasis is evident.

  • Addison’s disease, or hypoadrenocorticism, results from decreased corticosteroid and mineralocorticoid production from the adrenal glands. This results in non-specific signs of illness that mimic many other diseases. This article outlines screening and diagnostic tests for Addison’s disease.

  • Abdominal enlargement in dogs may occur due to a simple cause such as obesity, pregnancy, or intestinal parasites; however, it can also be a sign of different illnesses including hyperadrenocorticism, hypothyroidism, heart disease, organ enlargement trauma, GDV, and cancer. Identifying the cause of abdominal enlargement can take several steps starting with history and physical exam, progressing to screening tests including bloodwork and urinalysis. The CBC is assessed for signs of anemia, low platelets, or signs of inflammation. A biochemistry profile may reveal liver or kidney dysfunction, hypo- or hyperproteinemia, hypoglycemia, or other abnormalities. Urinalysis is used to fully interpret the biochemistry and check for abnormal urinary sediment. Based on the findings of the screening tests, additional diagnostics may include imaging, EKG, tissue biopsy, or fluid analysis.

  • Coughing can have many different causes, including infectious disease, heart disease, inflammatory conditions, anatomical abnormalities, or cancer. Important for the diagnosis is a thorough history, physical exam, and screening tests, outlined here. More advanced diagnostics are also summarized.

  • Listlessness and inappetence are vague signs that can occur in pets for many reasons, both physical and mental. Diagnosis starts with a thorough history and physical exam and may progress to screening tests, including a complete blood test, biochemistry profile, and urinalysis, as well as additional tests. This article outlines the typical tests for listlessness and inappetence.

  • Diarrhea can be a simple diagnosis or a complex one. A thorough history and physical exam may be enough to determine the cause; however, in less obvious cases, various tests may be needed. Pending the results, a treatment plan can be developed.

  • Fever of unknown origin is a term used for persistent fever in pets. It has many possible causes, including infection, immune-mediated disease, and cancer. Initial steps in diagnosis are history and physical exam, followed by standard screening tests, including a complete blood count, biochemistry profile, and urinalysis. Further testing may be indicated. This article outlines the typical tests.